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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RELA
All Species:
22.73
Human Site:
S316
Identified Species:
50
UniProt:
Q04206
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04206
NP_001138610.1
551
60219
S316
F
K
S
I
M
K
K
S
P
F
S
G
P
T
D
Chimpanzee
Pan troglodytes
XP_001170057
551
60215
S316
F
K
S
I
M
K
K
S
P
F
S
G
P
T
D
Rhesus Macaque
Macaca mulatta
XP_001113258
543
59608
S316
F
K
S
I
M
K
K
S
P
F
S
G
P
T
D
Dog
Lupus familis
XP_540850
542
59248
S316
F
K
S
I
M
K
K
S
P
F
N
G
P
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q04207
549
60193
S316
F
K
S
I
M
K
K
S
P
F
N
G
P
T
E
Rat
Rattus norvegicus
NP_954888
550
60249
S316
F
K
S
I
M
K
K
S
P
F
N
G
P
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506224
261
29575
L64
Q
C
V
K
K
R
D
L
E
Q
A
I
T
Q
R
Chicken
Gallus gallus
P98152
558
60053
A321
F
R
A
F
V
Q
R
A
P
L
P
G
L
E
P
Frog
Xenopus laevis
Q04865
527
59040
N316
F
K
H
Y
V
K
N
N
P
F
A
G
G
E
T
Zebra Danio
Brachydanio rerio
NP_001001839
455
51088
D258
F
R
T
P
P
Y
C
D
T
N
L
T
E
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15330
999
111533
Q352
P
D
E
D
L
F
Q
Q
I
L
R
L
D
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.6
91.1
N.A.
88.9
90.3
N.A.
41.3
51.9
52.4
48.6
N.A.
26.5
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98
93.6
N.A.
92.7
93.6
N.A.
44
62.9
65.1
61.5
N.A.
36.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
0
20
40
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
60
60
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
0
19
0
0
10
0
% A
% Cys:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
10
10
0
0
0
0
10
0
37
% D
% Glu:
0
0
10
0
0
0
0
0
10
0
0
0
10
19
19
% E
% Phe:
82
0
0
10
0
10
0
0
0
64
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
73
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
55
0
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
64
0
10
10
64
55
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
10
0
0
10
0
19
10
10
10
0
10
% L
% Met:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
10
0
10
28
0
0
0
0
% N
% Pro:
10
0
0
10
10
0
0
0
73
0
10
0
55
10
10
% P
% Gln:
10
0
0
0
0
10
10
10
0
10
0
0
0
10
0
% Q
% Arg:
0
19
0
0
0
10
10
0
0
0
10
0
0
0
10
% R
% Ser:
0
0
55
0
0
0
0
55
0
0
28
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
10
0
0
10
10
55
10
% T
% Val:
0
0
10
0
19
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _